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West Indian Medical Journal

Print version ISSN 0043-3144


HAMMOUD, D; EL HADDAD, B  and  ABDALLAH, J. Hypercalcaemia secondary to Hypervitaminosis A in a patient with chronic renal failure. West Indian med. j. [online]. 2014, vol.63, n.1, pp. 105-108. ISSN 0043-3144.

Vitamin A toxicity is a well-described medical condition with a multitude of potential presenting signs and symptoms. It can be divided into acute and chronic toxicity. Serum vitamin A concentrations are raised in chronic renal failure even with ingestion of less than the usual toxic doses. Hypercalcaemia can occasionally be associated with high levels of vitamin A but it is rare. In this report, we describe a 67-year old female patient with chronic kidney disease who was taking vitamin A supplements for approximately 10 years. The patient had worsening of her chronic kidney disease over the last years and developed chronic hypercalcaemia. Her vitamin A level was elevated with a daily intake of 7000 IU. The vitamin A supplement was stopped. A few months later, vitamin A level diminished substantially and serum calcium levels returned to normal.

Keywords : Chronic renal failure; hypercalcaemia; hypervitaminosis; kidney failure.

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