West Indian Medical Journal

Paediatric critical care: beyond the walls

Transfer of head-injured patients in Jamaica: is there a problem?

Head-injured patients are often transferred to the University Hospital of the West Indies (UHWI) for tertiary care. There is no standardized, agreed protocol governing their transfer. During the three-year period January 1998 to December 2000, 144 head injured patients were transferred to the UHWI from other institutions. They were 70% male, had a mean age of 34 years and spent a mean of 13 days in hospital. Eighteen per cent were admitted to the Intensive Care Unit, where they spent a mean of nine days. On arrival, mean pulse rate was 92 ± 22 beats/minute, mean systolic blood pressure was 130 ± 27 mmHg and mean diastolic was 76 ± 19mmHg. Twenty-eight per cent of patients had a pulse rate above 100/min on arrival and 13.8% had systolic blood pressure below 60 mmHg. The Glasgow Coma Scale score was unrecorded at the referring institution in 70% of cases and by the receiving officers at the UHWI in 23% of cases. Intubation was done on only half of those who were eligible. Junior staff members initiated and carried out transfers whenever this was documented. The types of vehicles and monitoring equipment used could not be determined in most instances. Fifty-eight per cent of patientshad minor head injuries, 12%, severe injury and 33%, associated injuries requiring a variety of surgical procedures by multiple specialties. Most patients (80.6%) were discharged home but 11.8% died in hospital. Transfer of head-injured patients, many with multiple injuries is not being performed in a manner consistent with modern medical practice. There is urgent need for implementation of a standardized protocol for the transfer of such patients in Jamaica.

Los pacientes con heridas en la cabeza son a menudo transferidos al Hospital Universitario de West Indies (UHWI) para su cuidado terciario. No existe ningún protocolo acordado en relación con las normas que deben regir la transferencia. En el trienio de enero de 1998 a diciembre 2000, 144 pacientes con heridas de cabeza, fueron transferidos al HUWI desde otras instituciones. El 70% de ellos eran varones de 34 años de edad promedio, y el período de permanencia en el hospital fue 13 días como promedio. El 18% fue ingresado en la Unidad de Cuidados Intensivos, donde permaneció un promedio de 9 días. Al llegar al hospital, su pulso medio era de 92 ± 22 pulsaciones/minuto, la presión arterial sistólica media era de 130 ± 27 mmHg, y la media diastólica de 76 ± 19 mmHg. El 28% de los pacientes tenía un ritmo de pulsaciones por encima de 100/min al momento del ingreso, y un 13.8% tenía la presión arterial sistólica por debajo de 60 mmHg. No había constancia de la aplicación de la Escala de Coma de Glasgow en las instituciones que remitieron a los pacientes en el 70% de los casos, ni por parte de los funcionarios médicos que recibieron a los pacientes en el HUWI en el 23% de los casos. La entubación se realizó solamente en la mitad de los pacientes elegibles. El personal subalterno inició y llevó a cabo las transferencias en todos los casos docu-mentados. En la mayor parte de los casos no fue posible determinar los tipos de vehículos ni el equipo de monitoreo utilizados. El 58% por ciento de los pacientes presentaba heridas menores de la cabeza, el 12% tuvo heridas graves, y un 33% acudió con heridas asociadas que requerían diversos procedimientos quirúrgicos de múltiples especialidades. La mayoría de los pacientes (80.6%) regresó de alta a sus casas, pero el 11.8% murió en el hospital. La transferencia de pacien-tes con heridas en la cabeza - muchos de ellos con lesiones múltiples - no se está realizando de manera consistente con la práctica médica moderna. Se necesita implementar de modo urgente un protocolo de normativas que rijan la transferencia de estos pacientes en Jamaica.

Microbial isolates from patients in an intensive care unit, and associated risk factors

A retrospective one-year analysis of blood, sputum and urine samples taken from all patients admitted for more than 48 hours to the Intensive Care Unit at the University Hospital of the West Indies (UHWI) was undertaken. Positive trapped sputum cultures were found in 50% of patients, positive blood cultures in 32.7% and positive urine cultures in 23.1%. Gram-negative organisms predominated especially Pseudomonas aeruginosa (41.3%) and Acinetobacter spp (33.5%). Coagulase-negative staphylococcus (20%) and streptococcus group D (18.7%) were the most common gram-positive organisms. The Acinetobacter spp showed marked resistance to most antibiotics except for meropenem (82.7% susceptibility) while P aeruginosa was most susceptible to ceftazidime (84.4%) and amikacin (89.1%). Both the coagulase-negative staphylococcus and streptococcus group D were relatively sensitive to amoxycillin/clavulanate (80.6% and 79.3% respectively). There was a high incidence of yeast found in sputum (27.1%) and urine (16.8%). Mechanical ventilation was a significant risk factor for developing a positive sputum culture (p = 0.01), this effect being particularly prominent in those ventilated for > 5 days. Central venous pressure lines significantly increased the risk of a positive blood culture (p = 0.005). This increase was seen particularly in those with CVP lines for > 7 days. Other risk factors for developing positive cultures included preadmission infection, antibiotic use just prior to ICU admission, increasing APACHE II score and increasing age.

Un análisis retrospectivo de muestras de sangre, esputo y orina tomadas a todos los pacientes ingresados por más de 48 horas en la Unidad de Cuidados Intensivos del Hospital Universitario de West Indies (HUWI) fue realizado por espacio de un año. Se hallaron cultivos de esputo positivos en 50% de los pacientes, cultivos de sangre positivos en el 32.7%, y cultivos de orina positivos en el 23.1%. Hubo predominio de organismos gram-negativos, en especial Pseudomonas aeruginosa (41.3%) y Acinetobacter spp (33.5%). Los estafilococos coagulasa-negativos (20%) y los estreptococos del grupo D (18.7%) fueron los organismos gram-positivos más comunes. Los Acinetobacter spp mostraron marcada resistencia a la mayoría de los antibióticos, salvo al meropenem (82.7% susceptibilidad), mientras P aeruginosa fue muy susceptible a la ceftazidima (84.4%) y a la amikacina (89.1%). Tanto el estafilococo coagulasa-negativo como el estreptococo del grupo D fueron relativamente sensibles a la amoxicilina/clavulanato (80.6% y 79.3% respectivamente). Se halló una alta incidencia de levadura en el esputo (27.1%) y la orina (16.8%). La ventilación mecánica fue un factor de riesgo importante para desarrollar un cultivo de esputo positivo (p = 0.01), siendo este efecto particularmente prominente en los ventilados por > 5 días. Las líneas de la presión venosa central aumentaron significativamente el riesgo de un cultivo de sangre positivo (p = 0.005), haciéndose este incremento particularmente evidente en aquellos con líneas de PVC por > 7 días. Otros factores de riesgo para el desarrollo de cultivos positivos incluyeron las infecciones previas a la admisión, el uso de antibióticos justo antes del ingreso a la UCI, el aumento de la puntuación APACHE II cuenta, y la edad avanzada.

The effect of hurricane Ivan on emergency department operations at the University Hospital of the West Indies

The objective of this study was to determine the impact of Hurricane Ivan on the operations of the Emergency Department (ED) at the University Hospital of the West Indies (UHWI). Hurricane Ivan, - a category four Hurricane - traversed the south coast of the island of Jamaica on September 10, 2004, causing damage to several parishes. The study design is a descriptive retrospective record-based incidence study of all admissions to the ED commencing at 8:00 am September 10, 2004 and ending at 12 midnight September 11, 2004, covering the period of the entire duration of the hurricane as well as immediately after. Injuries that took place during the hurricane, inclusive of gun-shot wounds (GSWs) represented 40% of the total patients seen. The types of admission are listed categorically as well as specific items to be considered in planning for potential disasters of higher magnitude. Overall, the coping mechanism of the ED at UHWI was adequate for this magnitude of disaster.

El objetivo de este estudio fue determinar el impacto del huracán Iván en las operaciones del Departamento de Emergencia (DE) en el Hospital Universitario de West Indies (HUWI). El huracán Iván - un huracán de categoría 4 - atravesó la costa sur de la isla de Jamaica el 10 de septiembre de 2004, causando daños en varias provincias. El diseño del estudio consiste en un estudio descriptivo y retrospectivo de incidencias, basado en los registros de todos los ingresos al DE, a partir de las 8:00 del 10 de septiembre de 2004, hasta las 12 de la noche del 11 de septiembre de 2004. Es decir, el estudio abarca todo el período de duración del huracán y el tiempo inmediatamente después. Las lesiones ocurridas durante el período del huracán - incluidas las heridas de bala - representaron el 40% del total de los pacientes atendidos. Se hace un listado de los tipos de ingresos por categoría así como de los artículos específicos a ser tomados en cuenta a la hora de hacer planes en relación con desastres potenciales de mayor magnitud. En general, los mecanismos operativos del DE del HUWI fueron adecuados para enfrentar un desastre de esta magnitud.

Judet quadricepsplasty for extension contracture of the knee

Extension contracture of the knee is a well known complication of severe femoral fractures, especially in the supracondylar region. Traditional management by the Thompson quadricepsplasty may result in a variable return of knee flexion and the possibility of significant extension lag. The Judet technique of quadricepsplasty offers the advantages of a controlled, sequential release of the intrinsic and then the extrinsic components limiting knee flexion and a reduced potential for iatrogenic quadriceps rupture or extension lag. The modified Judet quadricepsplasty has definite advantages over the Judet technique since it usually involves less soft tissue dissection and consequently less blood loss.

La contractura en extensión de la rodilla es una complicación bien conocida de las fracturas femorales severas, sobre todo en la región supracondilar. El tratamiento tradicional mediante la cuadricepsplastia de Thompson, puede traer como resultado un retorno variable de la flexión de la rodilla y la posibilidad de un intervalo de extensión significativo. La técnica de cuadricepsplastia de Judet ofrece como ventajas un accionar secuencial y controlado de los componentes intrínsecos y extrínsecos que limitan la flexión de la rodilla, así como un potencial reducido para la ruptura de los cuadriceps iatrogénicos y el intervalo de extensión. La cuadripcepsplastia de Judet modificada tiene ventajas definidas sobre la técnica de Judet, ya que usualmente involucra menos disección de tejido blando, y por consiguiente menos pérdida de sangre.

Carcinoma of the jejunum with multideposit peritoneal seeding, resection and intraperitoneal chemotherapy

Jejunal adenocarcinoma is rare, often presenting late with widespread intraperitoneal disease. Intraperitoneal chemotherapy (IPC) has been shown in non-randomized studies to improve the survival of patients presenting with intraperitoneal metastases from carcinoma of the colon, appendix and stomach and in primary peritoneal malignancies including mesothelioma and pseudomyxoma peritonei, providing that adequate operative cytoreduction can be performed. A case is presented of obstructive jejunal adenocarcinoma in which 19 intraperitoneal deposits were excised. The patient was treated successfully with immediate postoperative IPC followed by systemic chemotherapy. This condition is reviewed along with the rationale for IPC.

El adenocarcinoma del yeyuno es raro, presentándose a menudo de forma tardía con enfermedad intraperitoneal extensa. Estudios no randomizados han demostrado que la quimioterapia intraperitoneal (QIP) mejora la supervivencia de pacientes que presentan metástasis intraperitoneal del carcinoma de colon, apéndice y estómago, así como en malignidades peritoneales primarias, incluyendo el mesotelioma y el pseudomixoma peritoneal, siempre que se realice una adecuada citoreducción quirúrgica. Se presenta un caso de adenocarcinoma yeyunal obstructivo en el que se extirparon 19 depósitos del intraperitoneal, tratándose inmediatamente al paciente exitosamente con quimioterapia intraperitoneal postoperatoria, seguida de quimioterapia sistémica. Se examina esta condición junto con las razones para practicar la QIP.

Penetrating type intraosseous ganglion cyst of the lunate bone

Intraosseous ganglion cysts of the carpal bones located in the lunate are one of the rarely seen pathologic conditions. Here we present a case of the penetrating type of intraosseous ganglion cyst located in the lunate as an uncommon cause of wrist pain. The patient was successfully treated by surgical intervention. Intraosseous ganglion cyst should be considered in the differential diagnosis of chronic dull wrist pain.

Los gangliones intraóseos de los huesos carpianos localizados en el semilunar, constituyen una de las condiciones patológicas más raras que puedan verse. Aquí presentamos un caso del tipo penetrante de ganglión intraóseo, localizado en el semilunar como causa poco común del dolor de muñeca. El paciente fue tratado exitosamente mediante una intervención quirúrgica. El quiste ganglionar intraóseo debe ser considerado en el diagnóstico diferencial de dolores de muñeca sordos que se han hecho sentir por mucho tiempo, y se han vuelto crónicos.

**An in vitro comparison of implant materials, cell attachment, cytokine and osteocalcin production**

Bone deposition, for any implant system, is the deciding factor for the success. The biochemical signals at the cellular level will help elucidate the direction of host response. In this report, intercellular messenger, cytokines, that are regulatory for osteoblast and osteoclast function, were measured. Production of osteocalcin, a marker for osteoblast maturation was also estimated. Human osteoblastlike cells from osteosarcoma cell line MG 63 were grown in wells in the presence of titanium (Ti),titanium alloy (Ti6A14V) and stainless steel implant materials incubated at 37(0)C. Interleukin- 1 alpha(IL- 1 alpha), IL-6, IL-8, IL-11 and osteocalcin were quantitated using standard enzyme linked immunosorbant assay (ELISA) kits from the growth media extracted at specific intervals over the critical ten day period. In all dishes, cells were seen adhering to the base after 24 hours and to confluence at 96 hours. Both IL-1 a and IL-11 were not produced in sufficient quantities to be measured in the assay (< pg/ml). Interleukin-6 production was significantly higher for stainless steel than for titanium and the alloy. There was a progressive rise in osteocalcin production for titanium contrasted to a basal rate for stainless steel and alloy. Interleukin-8 levels for all metals and controls increased markedly after two days implicating inherent cellular characteristics. A relatively high constant range for macrophage colony stimulating factor from the first day was seen for all metals, including the controls. In conclusion, it appears that titanium implants activate osteocalcin production while stainless steel activates IL-6.

The comparative effectiveness of two digit-sucking deterrent methods

A study was conducted to compare the effectiveness of the crib and positive reinforcement in eliminating anterior open bites and increased overjets caused by digit-sucking. The overjet and overbite were measured using an overjet ruler at the start and end of the seventeen-week observation period. Forty patients consented to participate but measurements were only obtained for 11 subjects. The trend in this study is that the crib is more effective than positive reinforcement in preventing digitsucking.

A new surgical management for oro-antral communication: the resorbable guided tissue regeneration membrane - bone substitute sandwich technique

This paper describes a new technique for the closure of oro-antral fistula/communication, in which both hard tissue (bone) and soft tissue closure is achieved. The sandwich technique utilizes a suitable bone grafting material sandwiched between two sheaths of Biogide® (a resorbable membrane) for the hard tissue closure of oro-antral communication post traumatic exodontia. The bone grafting material utilized for this case was Bio-oss. The result obtained was excellent with regeneration of sufficient bony tissue to allow placement of an endosseous implant. This sandwich technique is a simple and excellent technique for the closure of oro-antral communication, especially when subsequent placement of endosseous implant is considered without the need of donor site surgery for bone grafting. The otorhinolaryngologists and oral and maxillofacial surgeons should find this technique very useful in the closure of oro-antral fistulae.

Cemento-osseous dysplasia in Jamaica: review of six cases

Six cases of cemento-osseous dysplasia (COD) of the jaw bone in Jamaicans are reviewed. Five were documented over a 15-year period (1980 - 1995). These include a case of florid cemento-osseous dysplasia (previously called gigantiform cementoma). Three of the initial cases were histologically diagnosed as gigantiform cementoma. There was no indication in the patient's case file whether these were familial or non-familial. The other two cases were diagnosed histologically as periapical cemento-osseous dysplasia and cementoblastoma respectively. Based on the current understanding of the nature of florid-cemento-osseous dysplasia (FLCOD), a new case was diagnosed as such solely on radiological findings. This single case of FLCOD is reported and discussed against the background of other cemento-osseous lesions. Special emphasis is placed on the radiology of COD in this paper. The confirmative role of radiology without the need for histophathology and treatment for asymptomatic FLCOD is emphasized.

**Ceftazidime-resistant Salmonella enteritidis in Jamaica**

Increased copper level in oral mucosal tissue of patients with submucous fibrosis and who chew areca nut products

Image and diagnosis

Ethical practice in everyday healthcare